Cholesterol is an important pharmaceutical intermediate, widely used in the production of vitamins D2, D3, artificial bezoar, synthetic hormones and anticancer drugs, as an additive and as a photochemical and electronic liquid crystal material. In practical applications, the purity of cholesterol is very high, especially the purity of pharmaceutical grade cholesterol is more stringent. High purity cholesterol is extracted from fish oil residues by the combined extraction centrifugal extractor, which not only improves production efficiency, but also ensures high purity and quality stability of the product.

** 1. Efficient operation of combined extraction centrifugal extractor in cholesterol extraction **

In the process of cholesterol extraction, it is necessary to saponify the fish oil residue with sodium hydroxide solution to prepare saponification solution. Next, the multistage countercurrent extraction of saponification liquid was carried out through a series continuous centrifugal extraction system with the mixture of n-heptane and ethyl acetate as extractant and acetic acid solution as detergent. The combined extraction centrifugal extractor plays a key role in this process, and its unique design and efficient centrifugal separation technology make the final cholesterol product purity ≥99%, meeting the strict requirements of pharmaceutical grade cholesterol.

Through its high speed rotation and strong centrifugal force, the cholesterol in the saponification liquid can be effectively separated from other impurities. The multistage tandem countercurrent design of the device ensures the gradual concentration and purification of cholesterol at each stage. By controlling the ratio of saponification solution, extractant and detergent to 2:1:1, the extraction process is further optimized, ensuring high purity and low impurity content of the final product.

** II. The innovative structure of the combined extraction centrifugal extractor responds to complex extraction requirements **

Complex components and various impurities in fish oil residues pose many challenges during cholesterol extraction. The combined extraction centrifugal extractor has successfully solved these technical problems through a series of innovative structural designs. The equipment is equipped with large aspect ratio design, CIP online cleaning system and weak stirring strong separation function, so that it can effectively adapt to the process requirements of cholesterol extraction.

The large aspect ratio design provides a larger centrifugal separation area, improves the separation efficiency, and enables a more thorough separation of cholesterol from other impurities. CIP in-line cleaning systems ensure the cleanliness of equipment during operation, reducing downtime and maintenance costs. The weak stirring and strong separation function effectively avoids emulsification and ensures the stability and high efficiency of the separation process. These technological innovations make the combined extraction centrifugal extractor not only perform well in cholesterol extraction, but also show a wide range of application potential in other complex biological extraction and chemical separation.

Through the application of the combined extraction centrifugal extractor, the extraction process of cholesterol has been significantly optimized, and the production efficiency and product quality have been greatly improved. Its high efficiency, automation and environmental protection characteristics make it an ideal choice in the field of cholesterol extraction, providing strong support for the sustainable development of the industry. The combined extraction centrifugal extractor not only performs well in cholesterol extraction, but also shows extensive application potential in other complex plant extraction and biological product separation.