Nicotine is the most important component of tobacco alkaloids, and has important applications in pesticide production, disease treatment and tobacco industry. The traditional nicotinic extraction process includes crushing tobacco leaves, water immersion, dilute acid soaking, filtration, concentration, pH adjustment to alkaline and solvent extraction. However, solvent extraction is a key step in the extraction process and determines the purity and yield of nicotine. The combined extraction centrifugal extractor plays an important role in this process, which significantly improves the extraction efficiency and product quality of nicotine.

** 1. Efficient operation of combined extraction centrifugal extractor in nicotine extraction **

In the key solvent extraction section of nicotinic extraction, the high-efficiency centrifugal extractor is operated by multi-stage series countercurrent operation, using n-hexane as extractant, O/A ratio is set between 1:2 and 1:4, and other process parameters are strictly controlled. After the five-stage extraction, the extraction rate can reach more than 99.5%, and the nicotine content in the residual solution is less than 0.1%. This process not only improves the purity and yield of nicotine, compared with the traditional extraction kettle, the performance of the combined extraction centrifugal extractor is more excellent, and the process realizes continuous, closed and automated operation, which greatly improves the production efficiency.

Through its high-speed rotation and strong centrifugal force, the combined extraction centrifugal extractor can effectively separate nicotine from solvent and form a series of high-efficiency centrifugal separation sections. The multistage series countercurrent design of the equipment ensures the gradual concentration and purification of nicotine molecules and effectively reduces the residue of impurities. N-hexane, as an extractant, has excellent selectivity and efficient dissolution ability. It is used in combination with the combined extraction centrifugal extractor to create an efficient and stable extraction environment.

** II. Solve the technical problems in the extraction process **

In the extraction process of plant active components, technical problems such as third phase, oligomer and emulsification are often encountered. To address these problems, the joint extraction centrifugal extractor provides excellent solutions through a series of innovative structural designs. The equipment is equipped with large aspect ratio, CIP online cleaning system and weak stirring strong separation function, which can effectively adapt to the process requirements of plant extraction.

The large aspect ratio design increases the effective area of centrifugal separation and improves the separation efficiency. The CIP in-line cleaning system ensures that equipment is kept clean during operation, reducing downtime and maintenance costs. Weak stirring and strong separation function can effectively avoid emulsification and ensure stable and efficient separation process. These technological innovations make the combined extraction centrifugal extractor not only perform well in nicotine extraction, but also widely used in traditional Chinese medicine, biology and other fields, and achieve remarkable results.

Through the application of combined extraction centrifugal extractor, the extraction process of nicotine has been significantly optimized, and the production efficiency and product quality have been greatly improved. Its characteristics of high efficiency, automation and environmental protection make it an ideal choice in the field of plant active ingredient extraction, providing strong support for the sustainable development of the industry.